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中間絲(英語:Intermediate filaments,IF,又譯中間纖維)直徑10奈米(nm)左右,介於7 nm的肌動蛋白微絲和25 nm的微管之間。 ... 與後兩者不同的是中間絲是最穩定的細胞骨架 ...
#2. What are intermediate filaments? | MBInfo
Keratin proteins comprise the two largest classes of intermediate filament proteins. Historically, the two types of keratin were grouped as acidic (type I) ...
#3. Keratin intermediate filaments in the colon - PubMed
由 L Polari 著作 · 2020 · 被引用 15 次 — Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the ...
#4. Types I and II Keratin Intermediate Filaments - Cold Spring ...
Keratins—types I and II—are the intermediate-filament-forming proteins expressed in epithelial cells. They are encoded by 54 evolutionarily conserved genes (28 ...
#5. Keratin intermediate filaments: intermediaries of epithelial cell ...
Keratins are grouped into type I and type II. Each keratin polypeptide consists of ∼310 amino acid-long central helical rod domain that is ...
#6. Intermediate Filaments at the Junction of ... - Frontiers
Typically keratin intermediate filaments are packaged into bundles called tonofibrils (Steinert et al., 1981a) and also form bifurcations ( ...
#7. Intermediate Filament - an overview | ScienceDirect Topics
Keratin intermediate filaments provide resilience to keratinocytes, the most abundant cell type in the epidermis. Keratins represent the largest group of ...
#8. Insights into the Dynamic Properties of Keratin Intermediate ...
The properties of keratin intermediate filaments (IFs) have been studied after transfection with green fluorescent protein (GFP)-tagged K18 and/or K8 (type ...
#9. Human keratin 1/10‐1B tetramer structures reveal a knob ...
To characterize keratin intermediate filament assembly mechanisms at atomic resolution, we determined the crystal structure of wild-type human ...
#10. Apoptosis and keratin intermediate filaments - Nature
The type I and type II keratins are the largest subgroups of the intermediate filament family. The keratins polymerize as obligate ...
#11. Keratin Intermediate Filaments and Diseases of the Skin
A major turning point came with the discoveries that mutations in keratin intermediate filament genes were responsible for a large number of inherited skin ...
#12. Micromechanical properties of keratin intermediate filament ...
Keratin intermediate filaments (KIFs) form cytoskeletal KIF networks that are essential for the structural integrity of epithelial cells.
#13. Modeling the Self-Organization Property of Keratin ...
Keratin intermediate filaments (IFs) fulfill an important function of structural support in epithelial cells. The necessary mechanical attributes require ...
#14. Ubiquitin-Proteasome-mediated Degradation of Keratin ...
We previously reported that shear stress induces phosphorylation and disassembly of keratin intermediate filaments (IFs). Shear stress also induces a time- ...
#15. 031-Intermediate Filaments - YouTube
#16. Structure and Mechanical Properties of Human Trichocyte ...
Keratin is a protein in the intermediate filament family and the key component of hair, nail, and skin. Here we report a bottom-up atomistic ...
#17. The Role of the Ubiquitin Proteasome Pathway in Keratin ...
... stimuli by reorganizing the cellular cytoskeleton, mainly accomplished through modification of the intermediate filament (IF) network.
#18. The keratin network of intermediate filaments regulates ...
Keratin intermediate filaments can further bundle together and undergo posttranslational phosphorylation and disulfide bonding to generate a complex ...
#19. Mechanical and signaling roles for keratin intermediate ...
We propose that maintenance of mechanical integrity in the mesendoderm by keratin intermediate filaments is required to balance stresses within ...
#20. The effects of actin cytoskeleton perturbation on keratin ...
Functional enrichment analysis revealed that five genes involved in keratin (KRT) intermediate filaments clustering in the chromosome 17q21.2 region, i.e., ...
#21. Complete Structure of an Epithelial Keratin Dimer - PLOS
Intermediate filaments (IF) are one of only three types of fibrous proteins in the human body. Keratins are the most numerous IF and are found ...
#22. Full article: Multiple roles for keratin intermediate filaments in ...
Multiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarity · abstract · Epithelial barriers, ...
#23. Model-based analysis of keratin intermediate filament assembly
The cytoskeleton of epithelial cells consists of three types of filament systems: microtubules, actin filaments and intermediate filaments (IFs).
#24. keratin intermediate filaments: Topics by Science.gov
Keratin intermediate filaments are abundant in epithelia and form cytoskeletal networks that contribute to cell type-specific functions, such as adhesion, ...
#25. Intermediate Filament Proteins and Their Associated Diseases
Intermediate filaments provide scaffolding for the cell and ... by the association of keratin mutations with end-stage liver disease.
#26. Cytoskeleton in motion: The dynamics of keratin intermediate ...
PDF | Epithelia are exposed to multiple forms of stress. Keratin intermediate filaments are abundant in epithelia and form cytoskeletal networks that.
#27. The Dynamics of Keratin Intermediate Filaments in Epithelia.
The organization of the keratin intermediate filament cytoskeleton is closely linked to epithelial function. To study keratin network plasticity and its ...
#28. Self-consistent field theory for the interactions between keratin ...
The intermediate filaments are represented by charged surfaces, ... chains can mediate a weak attraction between the keratin surfaces.
#29. Intermediate filaments: primary determinants of cell ... - JCI
Intermediate filaments (IFs) are major constituents of the cytoskeleton and nuclear ... containing an acidic SHC1 keratin and a basic SHC2 keratin (39, 40).
#30. Hexagonal Packing of Intermediate Filaments (Microfibrils) in ...
Electron micrographs of cross sections of highly oriented α-keratin fibers show the presence of intermediate filaments (IF) (microfibrils) packed parallel ...
#31. The human cell in intermediate filaments
Selection of proteins suitable as markers for the intermediate filaments or its substructures. Gene. Description. Substructure. KRT19, Keratin 19, Intermediate ...
#32. Shear Stress Induced Reorganization of the Keratin ...
Keratin intermediate filaments (KIFs) form a fibrous polymer network that helps epithelial cells withstand external mechanical forces.
#33. QuickGO::Term GO:0005882
Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of ...
#34. Self-consistent field theory for the ... - BMC Biophysics
Keratins are important structural proteins found in skin, hair and nails. Keratin Intermediate Filaments are major components of corneocytes ...
#35. Keratin intermediate filaments in the colon - X-MOL
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple layered columnar epithelium in the ...
#36. Keratin Intermediate Filaments as Regulators of Epithelial ...
Keratin intermediate filaments are cytoskeletal proteins regulating the polarity and intracellular organization of epithelial cells, ...
#37. Intermediate Filaments as Organizers of Cellular Space - MDPI
The expression of keratin intermediate filament proteins is a hallmark of epithelial differentiation. Keratins are subdivided into type I and type II ...
#38. Distribution of Keratin Intermediate Filaments in Cultured ...
Distribution of Keratin Intermediate Filaments in Cultured Thymic Epithelial Cells (TEC) is Dependent Upon Growth Medium Calcium Content - Volume 8 Issue ...
#39. Giant axonal neuropathy alters the structure of keratin ...
We used X-ray diffraction and tensile testing to determine potential changes to the structure of keratin intermediate filaments (IFs) in the ...
#40. 14-3-3 recruits keratin intermediate filaments to mechanically ...
The keratin intermediate filament network has been shown to be reorganized proximal to cell-cell adhesions in mesendoderm cells (Weber et ...
#41. Kinesin-dependent transport of keratin filaments: A unified ...
Keratin intermediate filaments (IFs) are the major cytoskeletal component in epithelial cells. The dynamics ofkeratinIFshavebeendescribedtodependmostlyonthe ...
#42. From ultra-soft slime to hard α-keratins: The many lives of ...
Intermediate filaments are filaments 10 nm in diameter that make up an important component of the cytoskeleton in most metazoan taxa. They are ...
#43. Elastic moduli of living epithelial pancreatic cancer cells and ...
... cancer cells (Panc-1), unusual amounts of keratin filaments can be found, ... cancer cells and their skeletonized keratin intermediate filament network.
#44. Intermediate filament Images, Stock Photos & Vectors
Cytoskeleton of a cell consists of microtubules, actin filaments and intermediate filaments. Keratin intermediate filament, chemical structure.
#45. Keratin | Sigma-Aldrich
Keratin 8 and keratin 18 (K8/K18) are intermediate filament proteins that form the obligate heteropolymers in hepatocytes and protect ...
#46. Intermediate filament proteins of digestive organs
Keratins are essential for Mallory-Denk body aggregate formation that occurs in association with several liver diseases, whereas an alternate type of keratin ...
#47. The Molecular Architecture for the Intermediate Filaments of ...
Most of these studies have been confined to one or two forms of alpha keratin. This high- and low-angle synchrotron fibre diffraction study extends the study to ...
#48. Proceedings of the Japan Academy, Series B - Intermediate ...
キーワード: intermediate filament, post-translational modification, ... Typically, vimentin filaments form a mesh-like network, whereas keratin filaments ...
#49. Keratin intermediate filament dynamics in cell heterokaryons ...
To study the dynamics of keratin intermediate filaments, we fused two different types of epithelial cells (PtK2 and. BMGE+H) and studied how the keratins ...
#50. Fillagrin and keratin intermediate filaments polymerise forming ...
During cornification a network of keratin intermediate filaments (KIF) and filaggrin (FLG) becomes crosslinked to the cornified envelope (CE).
#51. Self-consistent field theory for the interactions between keratin ...
Keratin Intermediate Filaments are major components of corneocytes, nonviable horny cells of the Stratum Corneum, the outermost layer of ...
#52. In Vitro Assembly and Structure of Trichocyte Keratin ...
In Vitro Assembly and Structure of Trichocyte Keratin Intermediate. Filaments: A Novel Role for Stabilization by Disulfide Bonding.
#53. Insights into the Dynamic Properties ... - AJOU Open Repository
Intermediate filaments (IFs)1 belong to a superfamily of ... type I and II keratins in vitro, specific pairs of keratin are expressed in epithelial cells in ...
#54. DISSECTING THE ROLE OF KERATIN INTERMEDIATE ...
DISSECTING THE ROLE OF KERATIN INTERMEDIATE FILAMENTS IN THE EARLY MAMMALIAN EMBRYO. ScholarBank@NUS Repository. Abstract: The cytoskeleton plays diverse ...
#55. Exploring the Mechanical Behavior of Single Intermediate ...
Intermediate filaments (IFs) are structural elements of eukaryotic cells with ... recombinant human keratin K5/K14 and neurofilaments isolated from.
#56. on the contribution of self-mediated organization of keratin ...
The crucial role of structural support fulfilled by keratin intermediate filaments (IFs) in surface epithelia likely requires that they be organized into ...
#57. Intermediate Filaments - Molecular Expressions Cell Biology
Intermediate filaments are a very broad class of fibrous proteins that play an important role as both structural and functional elements of the cytoskeleton.
#58. Intermediate Filaments | Biology for Majors I - Lumen Learning
Several types of fibrous proteins are found in the intermediate filaments. You are probably most familiar with keratin, the fibrous protein that strengthens ...
#59. Regulation of Expression of Keratins and their Pathogenic ...
Keratins are the member of intermediate filaments (IF), which composed of six subtypes ( · Keratin filaments are observed as tonofilaments under electron ...
#60. Rat Kangaroo Cell Intermediate Filaments with Cy2 - Nikon's ...
Rat kangaroo kidney (PtK2line) epithelial cells were immunofluorescently labeled with primary anti-keratin (an intermediate filament protein) mouse ...
#61. Learn About Keratin As Intermediate Filaments | Chegg.com
The keratin filaments are the important intermediatory filaments associated with the anchorage of the cells with the extracellular matrix through the employment ...
#62. Intermediate Filaments - Cell Biology and Cytochemistry
Types I and II: Acidic Keratin and Basic Keratin, respectively. · Type III. · Type IV Neurofilament H (heavy), M (medium) and L (low). · Type V are the lamins ...
#63. Intermediate Filaments | Basicmedical Key
The network of keratin filaments stabilizes the cell against physical forces and reinforces desmosomal attachments between cells. Scale bar is ˜ ...
#64. 中間絲(Intermediate filament) - 小小整理網站Smallcollation
一、簡介 1.直徑:10nm. Ÿ2.組成:由8根protofilaments圍成細繩狀;但是在不同的細胞內,胺基酸的組成順序都不同,換言之,不同的細胞有不同的intermediate filament, ...
#65. Cytoskeletal Intermediate Filaments - iBiology
Robert Goldman introduces us to cytoskeletal intermediate filaments, beginning with an overview of intermediate filament formation and properties.
#66. on the contribution of self-mediated organization of keratin ...
Corpus ID: 138473733. ON THE CONTRIBUTION OF SELF-MEDIATED ORGANIZATION OF KERATIN INTERMEDIATE FILAMENTS TO THEIR BIOLOGICAL FUNCTION IN ...
#67. Intermediate Filaments Function & Structure - Study.com
Keratin ; Desmin; Lamin; Vimentin; Neurofilaments. There are over fifty different proteins that make up intermediate filaments.
#68. Intermediate filaments - SlideShare
Intracellular Organization of Intermediate Filament Both keratin and vimentin attach to nuclear envelop serving to. Junction Proteins On ...
#69. Difference Between Tonofibrils and Tonofilaments
Intermediate filaments in epithelial cells are made from keratin protein. Tonofilaments are keratin intermediate filaments found in ...
#70. Intermediate Filaments - 第 361 頁 - Google 圖書結果
1990 , The two - chain coiled - coil molecule of native epidermal keratin intermediate filaments is a type I - type II heterodimer . J. Biol . Chem .
#71. Intermediate Filament Cytoskeleton - 第 127 頁 - Google 圖書結果
Apoptosis and keratin intermediate filaments . Cell Death Differ . 9 , 486-492 . Oshima , R. G. , and Baribault , H. ( 1992 ) . Inactivation of keratin ...
#72. Intermediate Filaments - 第 86 頁 - Google 圖書結果
Activation of keratin 19 gene expression by a 3' enhancer containing an AP1 ... Mitosis and intermediate-sized filaments in de- veloping skeletal muscle.
#73. Intermediate Filaments - Sumanas, Inc.
Intermediate Filaments. SOURCE: Alberts, et al., Molecular Biology of the Cell, Fifth Edition. Animation © 2008 Garland Science Publishing and Sumanas, Inc.
#74. International Review of Cell and Molecular Biology
Concurrent collapse of keratin filaments, aggregation of organelles, ... Micromechanical properties of keratin intermediate filament networks. Proc. Natl.
#75. Development of the Gastrointestinal Tract - 第 69 頁 - Google 圖書結果
Intermediate filaments formed de novo from tail - less cytokeratins in the cytoplasm ... Hatzfeld M , Weber K. Modulation of keratin intermediate filament ...
#76. Target Discovery and Validation: Reviews and Protocols
Coulombe, P. A. and Omary, M. B. (2002) 'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments.
#77. Epidermolysis Bullosa Market to Observe Stunning Growth by ...
... proteins within keratin intermediate filaments, focal adhesions, desmosome cell junctions, and hemidesmosome attachment complexes, ...
#78. What is an example of a polymer? - Quora
Polymers may be divided into two categories. Natural polymers (also called biopolymers) include silk, rubber, cellulose, wool, amber, keratin, collagen, ...
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