冰島的研究,新冠病毒抗體可在人體內維持4個月。
但是……
還是不清楚恢復健康的新冠肺炎患者體內的抗體是否能保護他們免受再次感染。
9月1日,由冰島 deCODE Genetics的研究團隊刊登於《新英格蘭醫學雜誌》的一篇最新研究說明,冰島90%以上的新冠肺炎患者在確診後體內抗體水平上升,隨後保持穩定,前後持續長達4個月的時間。
該研究團隊收集 30576 個冰島人(佔冰島總人口的 8.4%)的血清中抗體進行檢測。血清樣本來自......
1.從 1237 位在 4 個月內經由 qPCR 確診 新冠肺炎陽性的患者收集 2102 個血清樣本。
2.從曾經接觸確診患者(曾曝露於新冠病毒環境)而被隔離的民眾收集 4222 個血清樣本。
3.從23,452名未曾接觸確診患者(曝露於新冠病毒環境狀況不明)的民眾血清樣本。
研究團隊將血清樣本進行 6 種抗體檢測,包含 2 種泛免疫球蛋白。
研究調查結果:
大約有0.9%的冰島人口被感染了新冠病毒。而感染的致死率為0.3%。
在確診感染者中,56%曾接受qPCR實驗室檢測並被證實感染;有 14% 發生在隔離群體中,30% 發生在隔離區以外的群體中。
因此冰島有44%的新冠病毒感染者先前未被診斷。
重點在此......
研究人員報告指出,從新冠病毒感染中恢復過來的1797名患者中,接受檢測的1215名患者中有1107名(91.1%)是血清抗體陽性,而且通過qPCR診斷後的2個月內,患者抗病毒抗體水平增加,兩個月後則保持平穩水平。
在隔離人群中,有2.3%呈血清陽性。在未知接觸者中,有0.3%為陽性。
或許這篇研究僅是來自冰島一個國家的研究對象,在世界其他人口多樣化的地區,研究結果有可能不一樣。
但對照先前的研究,冰島 deCODE Genetics團隊這項新的研究發現,可能會對人類再次感染新冠肺炎的風險和新冠肺炎疫苗的耐久性產生一次新的審視評估。
但是呢 !
NEJM同一時間發表的一篇社論馬上警告說,目前還是不清楚恢復健康的新冠肺炎患者體內的抗體是否能保護他們免受再次感染。
nejm genetics 在 趙氏讀書生活 Facebook 的最佳解答
【#重要資訊請廣傳🇮🇹】日前中國官媒、微信、香港藍媒鋪天蓋地宣傳,「武漢肺炎源自意大利」,唯一的source,就是引述意大利醫生Giuseppe Remuzzi接受美國電台訪問的一句話,再斷章取義,昨天我們已經解釋過。
一位手足為了求真,專門發電郵向Dr Remuzzi本人詢問,從這位意大利專家的以下回覆,可明確知道他的原意:不但肯定武漢肺炎源自武漢,而且懷疑早在10月尾,武漢可能已出現武漢肺炎感染,但中國政府沒有公佈,期間可能大量中國人從武漢來到意大利,令意大利出現了一些疑似案例,由於一切來自中國的資訊都不透明,才令疫情失去控制的黃金時機。整個訊息,和中國官媒宣傳的完全相反,fake news之意,莫此為甚。
Dear XXX,
The only thing I said was that some general practitioners candidly told me of having observed a few cases of severe pneumonia already in late November and December, which is not unexpected, since the majority of contagions are coming from asymptomatic people who likely travelled from China before the Chinese authorities communicated that this outbreak had occurred. Attached is my answer to the journalists who have contacted me.
//Quoting the answer:
I repeat, none of these cases have been documented as Covid-19 because there was no evidence yet of the existence of Covid-19.
In any case, we can be certain that the virus emerged in Wuhan first, where it had probably been circulating for some time before it was made public in China, and the genetics confirm this beyond a shadow of a doubt. It arrived in Italy through a German person who had been in contact with a Chinese person, as you can see in the NEJM paper (DOI: 10.1056/NEJMc2001468). The strongest evidence of the fact that the current Covid-19 derives from bats and pangolins is reported in an article in Nature Medicine (https://doi.org/10.1038/s41591-020-0820-9) recently published, which shows almost identical sequences. Commercial activities using bats and pangolins are very well documented in Wuhan market, which was almost certainly the source of the outbreak. The question now is for how long the virus was circulating in China before health authorities understood the dimension of the problem. Considering the incubation period, I would not be surprised if asymptomatic individuals had been moving around China and travelling abroad in December and maybe even earlier.
In my opinion, there is no doubt that the virus arrived in Italy from China based on genetic studies just reported in Nature Medicine. However, one has to consider the possibility that, rather understandably, the emergence of this unfortunate event in China probably occurred long before health authorities realised it,considering the number of asymptomatic carriers, which isnow extremely well documented in the paper published in Science (DOI:10.1126/science.abb3221).//
By the way, I think you should probably investigate an event that was organised in Wuhan at the end of October (see attached). We know from the paper published in Science that 80% of contagions occur through people who are asymptomatic; you can imagine how many people arrived in Italy from Wuhan in that precise period of time.
Please see also a statement by Daniel Lucey, an infectious disease specialist at Georgetown University and the Lancet paper attached.
Best regards,
Giuseppe Remuzzi//
nejm genetics 在 堅離地城:沈旭暉國際生活台 Simon's Glos World Facebook 的最佳貼文
【#重要資訊請廣傳🇮🇹】日前中國官媒、微信、香港藍媒鋪天蓋地宣傳,「武漢肺炎源自意大利」,唯一的source,就是引述意大利醫生Giuseppe Remuzzi接受美國電台訪問的一句話,再斷章取義,昨天我們已經解釋過。
一位手足為了求真,專門發電郵向Dr Remuzzi本人詢問,從這位意大利專家的以下回覆,可明確知道他的原意:不但肯定武漢肺炎源自武漢,而且懷疑早在10月尾,武漢可能已出現武漢肺炎感染,但中國政府沒有公佈,期間可能大量中國人從武漢來到意大利,令意大利出現了一些疑似案例,由於一切來自中國的資訊都不透明,才令疫情失去控制的黃金時機。整個訊息,和中國官媒宣傳的完全相反,fake news之意,莫此為甚。
Dear XXX,
The only thing I said was that some general practitioners candidly told me of having observed a few cases of severe pneumonia already in late November and December, which is not unexpected, since the majority of contagions are coming from asymptomatic people who likely travelled from China before the Chinese authorities communicated that this outbreak had occurred. Attached is my answer to the journalists who have contacted me.
//Quoting the answer:
I repeat, none of these cases have been documented as Covid-19 because there was no evidence yet of the existence of Covid-19.
In any case, we can be certain that the virus emerged in Wuhan first, where it had probably been circulating for some time before it was made public in China, and the genetics confirm this beyond a shadow of a doubt. It arrived in Italy through a German person who had been in contact with a Chinese person, as you can see in the NEJM paper (DOI: 10.1056/NEJMc2001468). The strongest evidence of the fact that the current Covid-19 derives from bats and pangolins is reported in an article in Nature Medicine (https://doi.org/10.1038/s41591-020-0820-9) recently published, which shows almost identical sequences. Commercial activities using bats and pangolins are very well documented in Wuhan market, which was almost certainly the source of the outbreak. The question now is for how long the virus was circulating in China before health authorities understood the dimension of the problem. Considering the incubation period, I would not be surprised if asymptomatic individuals had been moving around China and travelling abroad in December and maybe even earlier.
In my opinion, there is no doubt that the virus arrived in Italy from China based on genetic studies just reported in Nature Medicine. However, one has to consider the possibility that, rather understandably, the emergence of this unfortunate event in China probably occurred long before health authorities realised it,considering the number of asymptomatic carriers, which isnow extremely well documented in the paper published in Science (DOI:10.1126/science.abb3221).//
By the way, I think you should probably investigate an event that was organised in Wuhan at the end of October (see attached). We know from the paper published in Science that 80% of contagions occur through people who are asymptomatic; you can imagine how many people arrived in Italy from Wuhan in that precise period of time.
Please see also a statement by Daniel Lucey, an infectious disease specialist at Georgetown University and the Lancet paper attached.
Best regards,
Giuseppe Remuzzi//