關於 rap1 protein telomeric ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. Rap1 Affects the Length and Heterogeneity of Human ...

The telomere length phenotypes of hRap1 deletion mutants implicated both the BRCT and Myb domain as protein interaction domains involved in telomere length ...

#12. DNA binding modes influence Rap1 activity in the regulation ...

Crystal structures have shown that Rap1DBD binds telomere repeat DNA in a sequence‐specific fashion through both the Myb-like motifs, which make ...

#13. Telomere-dependent and telomere-independent roles of ...

RAP1 is a well-known telomere-binding protein, but its functions in human stem cells have remained unclear. Here we generated RAP1-deficient ...

#14. TRF2-interacting telomeric protein/Rap1, C ... - EMBL-EBI

This family of proteins represents the C-terminal domain of the protein Rap-1, which plays a distinct role in silencing at the silent mating-type loci and ...

#15. RAP1 | SGD - Saccharomyces Genome Database

Rap1p is the major double-stranded telomeric repeat-binding protein in budding yeast and has essential roles in telomere length regulation, subtelomeric gene ...

#16. The telomeric protein Rap1 is conserved in vertebrates and is ...

Abstract. We have identified the chicken homolog of the mammalian telomere protein repression and activation protein 1 (Rap1). Although cRap1 has only 36% ...

#17. A RAP1-interacting protein involved in silencing and telomere ...

PDF | The yeast RAP1 protein is a sequence-specific DNA-binding protein that functions as both a repressor and an activator of transcription. RAP1 is.

#18. RAP1 - Rap1p - WikiGenes

Saccharomyces cerevisiae multifunctional protein RAP1 binds to a ... have a sub-nuclear localization similar to the telomere-associated RAP1 protein, ...

#19. Role of Rap1 in DNA damage response

Mammalian Rap1 is a part of the telomere binding complex named shelterin and is one of the most conserved telomeric proteins. With its essential requirement ...

#20. The human Rap1 protein complex and modulation of telomere ...

Mammalian telomere length is regulated by a number of proteins including human repressor activator protein (hRap1), a known association factor of TRF2.

#21. PomBase - protein coding gene - rap1 (SPBC1778.02)

PomBase - protein coding gene - rap1 (SPBC1778.02) - shelterin complex telomere binding subunit Rap1.

#22. RAP1 Is Essential for Silencing Telomeric Variant Surface ...

brucei telomere-specific protein (Li et al., 2005). Another mammalian telomeric protein is. RAP1, which does not contact DNA but is recruited to ...

#23. Literature citations | UniProt

Rif1 and Rif2, along with Rap1, form the telosome, a protective cap that inhibits ... Telomere length regulator protein RIF1 · Gene: RIF1 ...

#24. Identification of Human Rap1: Implications for Telomere ...

Identification of Human Rap1: Implications for. Telomere Evolution telomeres in budding yeast. Similarly, TIN2 and tankyr- ase, proteins ...

#25. RAP1 at the Yeast Telomere | Lund University

Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most ...

#26. Human Rif1 protein binds aberrant telomeres and aligns ...

Although there is a human Rap1 orthologue (hRap1) which localizes at telomeres and regulates telomere length like S. pombe Rap1p, it does not ...

#27. RAP1 Polyclonal Antibody (PA1-41267)

The hRap1 protein does not interact with TRF1. TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length(1). TRF2, like TRF1 ...

#28. Analysis of the <i>RAP1</i> protein binding to homogeneous ...

The telomeric DNA is assembled with DNA-binding proteins into a terminal nucleoprotein chromatin complex, where separate telomere-binding ...

#29. The DNA-Binding Domain of Yeast Rap1 Interacts with ...

Repressor-activator protein 1 (Rap1) from budding yeast Saccharomyces cerevisiae is an essential regulator of transcription and telomere ...

#30. Involvement of the Silencer and UAS Binding ... - Science

Several rap1ts alleles reduced telomere length in a temperature-dependent manner. In addition, plasmids that contain small, synthetic telomeres with intact or ...

#31. Rif1: A Conserved Regulator of DNA Replication and Repair ...

Rap1 -interacting factor 1 (Rif1) was originally identified in the budding yeast Saccharomyces cerevisiae as a telomere-binding protein that ...

#32. Involvement of the Silencer and UAS Binding Protein ... - JSTOR

in a complex fashionl. The changes in telomeric length observed in the rap 1 mutants also occurred in the X class of telomeres ( ...

#33. 1IGN: DNA-BINDING DOMAIN OF RAP1 IN ... - RCSB PDB

cerevisiae, telomeric DNA is bound in a sequence-specific manner by RAP1, a multifunctional protein also involved in transcriptional regulation ...

#34. TALEN gene knockouts reveal no requirement for the ...

The conserved protein Rap1 functions at telomeres in fungi, protozoa, and vertebrates. Like yeast Rap1, human Rap1 has been implicated in telomere length ...

#35. Telomere-binding protein - Wikipedia

The DNA-binding proteins include TERF1, TERF2, and POT1, which have specific sequences, altering binding affinity or regulatory mechanisms. TIN2, RAP1, TPP1 are ...

#36. Identification of Human Rap1: Implications for ... - Infona.pl

It has been puzzling that mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in budding yeast.

#37. RAP1 蛋白

RAP1 蛋白. (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP)). The gene encodes a protein that is part of a complex involved in telomere ...

#38. ACD Gene - GeneCards | ACD Protein | ACD Antibody

This gene encodes a protein that is involved in telomere function. ... between a multitude of telomeric factors, including telomerase, TRF1, TRF2, RAP1, ...

#39. Genome-wide studies of telomere biology in budding yeast

Rap1 : Rap1, an essential DNA binding protein, recognizes and binds to the yeast telomeric DNA repeats, and serves to determine telomere length by a “counting” ...

#40. RAP1 siRNA (h): sc-38554 - Santa Cruz Biotechnology

RAP1, also known as TERF2IP (telomeric repeat-binding factor 2-interacting protein 1) or DRIP5, is a 399 amino acid nuclear and cytoplasmic protein that.

#41. Human Gene TERF2IP (ENST00000300086.5) from ...

Description: Homo sapiens TERF2 interacting protein (TERF2IP), ... AF262988 - Homo sapiens TRF2-interacting telomeric RAP1 protein (RAP1) mRNA, complete cds ...

#42. TERRA and Telomere Maintenance in the Yeast ... - MDPI

Telomeres are structures made of DNA, proteins and RNA found at the ends of ... At telomeres, Rap1 recruits Rif1/2 proteins, which contribute to telomere ...

#43. Telomere-binding proteins Taz1 and Rap1 regulate DSB ...

Telomere -binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast.

#44. Active Motif Technical Data Sheet (TDS)

Background: RAP1 / TERF2IP (Repressor/activator protein 1, Telomeric repeat-binding factor 2-interacting protein 1) is a protein associated with telomeres ...

#45. The Evolving Telomeres - 第 17 頁 - Google 圖書結果

Mammalian Rap1 controls telomere function and gene expression through binding ... Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in ...

#46. The Cell Cycle: Principles of Control - 第 85 頁 - Google 圖書結果

Z, which blocks local spreading of Sir proteins by some unknown mechanism. ... the protein Rap1, which binds specifically to the telomeric DNA sequence.

#47. Chromosomal Instability and Aging: Basic Science and ...

... on proteins related to the Ku protein's function at the telomere. Telomeric DNA is shown as lines. (A) Rap1 and Sir4 may form a complex at the telomere.

#48. Genome Duplication - Google 圖書結果

of replication is necessary for activation of telomerase on the telomeres of a ... Rap1 (the human ortholog of the yeast repressor/activator protein 1), ...

#49. Chromatin: Structure & Function - 第 82 頁 - Google 圖書結果

These are binding sites for a non-histone protein known as RAP1 (Conrad et al., 1990). Although some lower eukaryotic telomeres have a nucleosomal ...

#50. Oxford Textbook of Cancer Biology - 第 211 頁 - Google 圖書結果

The telomeric DNA binding protein complex (shelterin) and DNA damage response ... The shelterin complex is made up of six family members: TRF1, TRF2, RAP1, ...

#51. Issues in Life Sciences: Cellular Biology: 2011 Edition - Google 圖書結果

(2010 MAY 3) Rockefeller University, New York City: Taking apart Rap1 An adaptor protein with telomeric and nontelomeric functions “Mammalian Rap1, ...

#52. Chromosomes Today: Volume 14

Telomeric localization of TRF2, a novel human telobox protein. ... Telomere binding of the Rap1 protein is required for meiosis in fission yeast.