關於 zoe-70 ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. 北醫藥訊 - 臺北醫學大學附設醫院

以下為一項針對之前兩大樞紐試驗(ZOE-50 和ZOE-70)受試者內有接種過以 glycoprotein E (IgE)為佐劑的重組帶狀皰疹疫苗(RZV)且年齡≥50 歲的人，接種6 ...

#12. (PDF) The Adjuvanted Recombinant Zoster Vaccine Confers ...

e cacy trials (ZOE-50 and ZOE-70). e present interim analysis was performed a er ≥2 additional years of follow-up (between.

#13. A post-hoc analysis of the ZOE-50 and ZOE-70 randomized trials

Efficacy of the adjuvanted recombinant zoster vaccine (RZV) by sex, geographic region, and geographic ancestry/ethnicity: A post-hoc analysis of the ZOE-50 ...

#14. 97.2% ZOE-702, ≥70 YOA ZOE-501, ≥50 YOA VE against ...

We present, for the first time, efficacy, immunogenicity persistence and safety data up to 10 years after initial vaccination (in ZOE-501 and ZOE-702) ...

#15. a sub-cohort analysis of the ZOE-50 and ZOE-70 randomized ...

In two large clinical trials (ZOE-50 [NCT01165177] and ZOE-70 [NCT01165229]), two doses of the adjuvanted recombinant zoster vaccine (RZV) ...

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#17. Safety of the adjuvanted recombinant zoster vaccine in adults ...

A phase IIIB, non-randomized, multinational, open-label study in previous ZOE-50 and ZOE-70 placebo recipients.

#18. Related content - Cochrane Library

Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older ... 50 years of age: a sub-cohort analysis of the ZOE-50 and ZOE-70 ...

#19. 新藥介紹：Zoster Vaccine Recombinant,Adjuvanted (Shingrix®)

ZOE -50/70 參與者以1:1 的比例隨機接受2. 劑疫苗或安慰劑，其中至少接受1 劑疫苗的. 參與者有資格被納入這項LTFU 研究。此試. 驗模式為開放性(open-label)、臨床第三B 期.

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#21. 114. Long-term Protection Against Herpes Zoster (HZ ... - X-MOL

VE analysis for ZOSTER-049 used historical control estimates from the ZOE-50/-70 placebo groups. Results In ZOSTER-049, 7,413 participants were ...

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#23. Medline ® Abstract for Reference 18 of '接种疫苗预防带状疱疹'

We present immunogenicity results from those trials. Methods Participants (ZOE-50:≥50; ZOE-70:≥70 years of age) received 2 doses of HZ ...

#24. Shingrix - Medsafe

studies (ZOE-50 and ZOE-70) involving 29,305 subjects aged 50 years and older who received at least one dose of SHINGRIX (n = 14,645) or saline placebo (n ...

#25. Recombinant Zoster Vaccine Is Efficacious and Safe in Frail ...

Of 29,305 participants from the pooled ZOE-50 and ZOE-70 total vaccinated cohort, 92% were included in this study. Mean age was 68.8 years; ...

#26. Efficacy Data - Shingrix

Cunningham AL, Lal H, Kovac M, et al, for the ZOE-70 Study Group. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med ...

#27. Prevention of Herpes Zoster: A Focus on the Effectiveness and ...

Efficacy and effectiveness of the recombinant zoster vaccine (RZV) in adults. Table. ZOE-70 was a similarly designed, randomized, placebo-controlled clinical ...

#28. Natural History of Herpes Zoster in the Placebo Groups of ...

An estimated 12.3%, 16.9%, and 21.8% of patients in the ZOE-50, ZOE-70, and ZOE-HSCT studies, respectively, developed post-herpetic neuralgia.

#29. Anhang zur wissenschaftlichen Begründung für die ... - RKI

In The ZOE 50 and ZOE70. Cohort Vaccine efficacy did not differ significantly between the two age groups. (91.3% in participants 70 to 79 years of age and 91.4% ...

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#31. Recombinant Zoster Vaccine Efficacy Appears Durable

In two prior placebo-controlled, manufacturer-funded trials (ZOE-50 and ZOE-70), the vaccine exhibited ≥97% efficacy after 3.2 years in ...

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#34. Shingrix, INN Herpes zoster vaccine (recombinant, adjuvanted)

284 cases in the pooled analysis of ZOE-. 50 and ZOE-70). Table 1: Shingrix efficacy against HZ. Age. (years). Shingrix. Placebo. Vaccine efficacy. (%).

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#36. Quality of Life Impact of an Adjuvanted Recombinant Zoster ...

In confirmed HZ cases, adjuvanted recombinant zoster vaccine reduced the maximal ZBPI worst-pain score in the pooled ZOE-70 analysis (p = .032) and the maximal ...

#37. Herpes zoster subunit vaccine safe and highly effective in ...

... herpes zoster and postherpetic neuralgia (PHN) in adults over age 70. ... safe and highly effective in adults over 70: The ZOE-70 trial.

#38. Recombinant Zoster Vaccine May Attenuate Pain Symptoms ...

The efficacy for reducing pain medication use was significant for the ZOE-70 trial data (vaccine efficacy [VE], 39.6%; 95% CI, 10.8-64.8; ...

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#41. Vaccine Efficacy After One Dose of Shingrix in Adults ≥ 50 ...

One study (ZOE-50 study)(1) included adults ≥ 50 years of age [N = 7698 (HZ/su group) and N = 7713 (placebo group)], the second study (ZOE-70 study)(2) ...

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#44. La vacuna recombinante adyuvada frente al herpes zoster ...

... Protection Against Herpes Zoster: Interim Results of an Extension Study of the Pivotal Phase 3 Clinical Trials ZOE-50 and ZOE-70.

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#46. Adjuvanted recombinant zoster vaccine decreases herpes ...

Although a similar trend was observed in the ZOE-50 and ZOE-70 studies, the results were not statistically significant because of the high vaccine efficacy ...

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#48. GSK's phase III study of shingles vaccine, Shingrix shows 90 ...

The ZOE-70 (ZOster Efficacy in adults aged 70 years and over) (NCT01165229) study is a randomised, observer-blind, placebo-controlled (saline solution) ...

#49. FDA Panel Recommends New Shingles Vaccine - Medscape

For ZOE-70, HZ vaccine effectiveness was 89.79% (95% CI, 84.29% - 93.66%). For ZOE-50, 18 cases of PHN occurred in the placebo group compared ...

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#51. The Adjuvanted Recombinant Zoster Vaccine Confers Long ...

... Confers Long-Term Protection Against Herpes Zoster: Interim Results of an Extension Study of the Pivotal Phase 3 Clinical Trials ZOE-50 and ZOE-70.

#52. Efficacy of the Herpes Zoster Subunit Vaccine in ... - UQ eSpace

Adults 70 Years of Age or Older [ZOE-70]) to as- sess vaccine efficacy against herpes zoster in this population; we also estimated vaccine ...

#53. LL MenConsult 113017 - Concierge Medicine of Cincinnati

In ZOE-70, a study in adults aged 70 years or older, vaccine efficacy was 89.8%.14. In pooled analysis, Shingrix vaccine efficacy.

#54. A Pooled Post-hoc Analysis on Two Parallel Randomized Trials

In 2 pivotal studies, ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229), the adjuvanted recombinant zoster vaccine (RZV) proved to be efficacious against HZ in ...

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#56. Efficacy of Herpes Zoster Vaccine in Older Adults - MDedge

Vaccine efficacy against herpes zoster and postherpetic neuralgia was assessed in participants from the trial of adults aged ≥70 years (ZOE-70) ...

#57. The ZOE Trials - Herpes Zoster Recombinant Subunit Vaccine

Very similar findings were observed in ZOE-70. See pooled results in Table 1. Unlike the previous live-attenuated product, the HZ subunit vaccine was effective ...

#58. Non-Live Recombinant Herpes Zoster Vaccine (SHINGRIX)

Two Studies: Efficacy of the Herpes Zoster Subunit Vaccine: in Adults 70 years of age or older (ZOE-70) 2016 & in Older Adults (ZOE-50) 2015.

#59. A new herpes zoster subunit vaccine for older adults. - CORE

In another prespecified pooled analysis of ZOE-50 and ZOE-70 trial participants aged ≥50 years, VE against post-herpetic neuralgia was 88.8% (95% CI 68.7-97.1 ...

#60. SHINGRIX (recombinant Varicella Zoster Virus glycoprotein E ...

In ZOE-50 and ZOE-70, the immunogenicity of SHINGRIX was evaluated up to Month 38 (3 years post-dose 2). The humoral immunogenicity and CMI ...

#61. Vaccine for the Prevention of Herpes Zoster

1 ZOE-70 included 13 900 patients aged ≥70 years. Efficacy was 89.8% (95% CI, 84.2–93.7%; P<.001) for prevention of herpes zoster and ...

#62. Recommendations of the Advisory Committee on ...

... it was modeled that RZV effectiveness in adults aged 50–69 years or ≥70 years ... for Zoster Efficacy Study in Adults 70 Years of Age or Older (ZOE-70).

#63. GSK's candidate vaccine has 90% efficacy against shingles

Based on the data of ZOE-70 and ZOE-50, GSK intends to submit a regulatory application for Shingrix, in order to prevent shingles in people aged ...

#64. Efficacy of the herpes zoster subunit vaccine in adults 70 ...

A complete list of investigators in theZoster Efficacy Study in Adults 70 Years of Age or Older (ZOE-70) Study Group is provided in the ...

#65. Medical conditions at enrollment do not impact efficacy and ...

In two pivotal efficacy studies (ZOE-50; ZOE-70), the adjuvanted recombinant zoster vaccine (RZV) demonstrated >90% efficacy against herpes zoster (HZ).

#66. New Herpes Zoster Vaccine Highly Effective in Older Adults

... in preventing herpes zoster in the ZOE-50 and ZOE-70 trials” involving patients older than age 50 and 70 years, respectively.

#67. Adjuvanted Zoster Vaccine: Persistent Protection - Relias Media

Boutry et al reported the interim results of a follow-up study of adults older than age 50 years enrolled in two pivotal trials (ZOE-50/70) ...

#68. Herpes Zoster - Immunisation Coalition

Chair, Publications Committee, GSK Shingrix ZoE50 and ZoE70 trials ... ZOE 50/70 efficacy studies conducted at the same sites. Subjects ≥70 years of age ...

#69. A new herpes zoster subunit vaccine for older adults - Nature

In another prespecified pooled analysis of. ZOE-50 and ZOE-70 trial participants aged. ≥50 years, VE against post-herpetic neuralgia was 88.8% ...

#70. Herpes zoster subunit vaccine for the prevention of herpes ...

While ZOE-50 and ZOE-70 were large, multicenter trials with a randomized, placebo- controlled design, there are a few limitations to note. First ...

#71. 싱그릭스 3상 ZOE-50·ZOE-70 데이터로 본 '예방률 97%' - 팜뉴스

... 있다.11일 팜뉴스는 재조합 항원과 면역증강제 결합 첫 번째 대상포진 백신인 싱그릭스 주요 임상 연구 ' ZOE-50', 'ZOE-70' 데이터를 소개한다.

#72. 23. Zoster (herpes zoster/shingles) – Immunisation Handbook ...

Two phase III clinical trials (ZOE-50 and ZOE-70) demonstrated vaccine efficacy of over 90 percent in adults aged from 50 years and aged ...

#73. The Adjuvanted Recombinant Zoster Vaccine Confers Long ...

... Confers Long-Term Protection Against Herpes Zoster: Interim Results of an Extension Study of the Pivotal Phase 3 Clinical Trials ZOE-50 and ZOE-70.

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#76. Efficacy of the Herpes Zoster Subunit ... - Read by QxMD

BACKGROUND: A trial involving adults 50 years of age or older (ZOE-50) showed that the herpes zoster subunit vaccine (HZ/su) containing recombinant varicella- ...

#77. Recombinant varicella zoster virus glycoprotein E antigen ...

ZOE-50 and ZOE-70, the efficacy of the recombinant vaccine did not appear to decline with increasing age. It was similar in all age groups (50– ...

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#80. Original article - Semantic Scholar

In the ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials, the adjuvanted re- combinant zoster vaccine (RZV) demonstrated ...

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#82. GSK帶狀皰疹疫苗(HZ/su)的第三期臨床實驗結果(ZOE-70)

GSK藥廠的帶狀皰疹疫苗(HZ/su)在70歲以上族群的第三期臨床實驗結果(ZOE-70). 13900人納入研究後被分作實驗組（兩個月打一劑疫苗共打兩劑）及對照組（ ...

#83. GSK's candidate shingles vaccine demonstrates 90% efficacy ...

The ZOE-70 (ZOster Efficacy in adults aged 70 years and over) study is a randomised, observer-blind, placebo-controlled (saline solution) ...

#84. Effect of Recombinant Zoster Vaccine on Incidence of Herpes ...

The Zoster Efficacy Study in Patients Undergoing HSCT (ZOE-HSCT) was ... Cunningham AL, Lal H, Kovac M, et al; ZOE-70 Study Group.

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#86. Zoster Vaccines in Older Adults

Design: Randomized, double-blind, placebo- controlled, stratified by age, 60-69 and ≥ 70 ... ZOE-50 Adverse Events and Reactogenicity.

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一项涉及50岁或以上的成年人试验（ZOE-50）表明，与安慰剂相比，含有重组水痘带状疱疹病毒糖蛋白E和AS01B佐剂系统的带状疱疹亚单位疫苗（HZ/su）可 ...

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