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在antifungal drugs這個產品中，有5篇Facebook貼文，粉絲數超過37萬的網紅范琪斐的美國時間，也在其Facebook貼文中提到， 有關昨天立百病毒的新聞影片，在這裡有兩點更正： 1.影片中提到「立百病毒具有抗生素抗藥性」，引用的來源英文原文是antimicrobial resistance（AMR）。 這裡我們的團隊犯了一個錯誤，AMR的中文通常直譯為「抗生素抗藥性」，但中文的抗生素指的通常是Antibiotics，多數情...

antifungal drugs 在 范琪斐的美國時間 Facebook 的最讚貼文

范琪斐的美國時間 By 范琪斐的美國時間

2021-02-04 16:31:37 有 1,408 人按讚
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有關昨天立百病毒的新聞影片，在這裡有兩點更正：

1.影片中提到「立百病毒具有抗生素抗藥性」，引用的來源英文原文是antimicrobial resistance（AMR）。

這裡我們的團隊犯了一個錯誤，AMR的中文通常直譯為「抗生素抗藥性」，但中文的抗生素指的通常是Antibiotics，多數情況下是針對細菌感染使用的抗生素。

而英文原文的antimicrobial ，WHO的用法範圍較廣，包含抗病毒藥物antiviral drugs、抗真菌劑antifungal agent等等，也包含在antimicrobial的範圍內。

對於 antimicrobial resistance 這個詞，WHO的中文正式譯名應該是「抗微生物藥物抗藥性」。由於我們在翻譯上的疏漏，給各位讀者「抗生素也對立百病毒有用嗎？」的錯誤觀念，在這邊要特別更正並致歉。

2.另一個會造成誤會的點是，藥品可及性基金會（Access to Medicine Foundation）以及WHO提出警告的公衛風險中，會產生抗藥性的並不只立百病毒，還有多重抗藥性結核桿菌 (MDR-TB) 、抗藥性人類免疫不全病毒 (HIVDR) ，以及裂谷熱、茲卡病毒等缺少有效新藥的傳染病。

原文將「抗微生物藥物抗藥性(AMR)」只跟立百病毒做連結的陳述方式，過度限縮了藥品可及性基金會的警告，在此要加以澄清，不是只有立百病毒有抗藥性的問題喔！

感謝各位網友的批評指教！

WHO有關AMR的說明：
https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance

衛報的原始系列報導：
https://www.theguardian.com/science/2021/jan/26/pharmaceutical-giants-not-ready-for-next-pandemic-report-warns

藥品可及性基金會的網站：
https://accesstomedicinefoundation.org

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范琪斐的美國時間

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資深駐美特派記者范琪斐，一個生活在紐約二十多年的臺灣媒體人，長期觀察臺美兩地文化差異。Podcast節目《說故事的人》各大平台皆可收聽。
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antifungal drugs 在 范琪斐的美國時間 Facebook 的精選貼文

范琪斐的美國時間 By 范琪斐的美國時間

2021-02-03 20:00:44 有 4,043 人按讚
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非營利組織「#藥品取得基金會」（Access to Medicine Foundation）一月底提出一份報告，點名致死率高達75%的「#立百病毒」（Nipah virus），很可能會是下一場大流行病的導火線。立百病毒不但致死率高，還具有抗藥性，可說是無藥可醫，這個病毒到底是何方神聖呢？

更正啓事：有關本集「立百病毒」新聞影片，有兩點更正：

1. 影片中提到「立百病毒具有抗生素抗藥性」，引用的英文來源是 Antimicrobial Resistance（AMR）。

我們的團隊犯下一個錯誤，AMR 的中文直譯是「抗生素抗藥性」沒錯，但中文的「抗生素」指的通常是 Antibiotics，多數情況下是針對細菌感染使用的「抗生素」。

而英文原文的 Antimicrobial ，據 WHO 的說法包含範圍較廣，包含抗病毒藥物 Antiviral Drugs、抗真菌劑 Antifungal Agent 也包含在內。

由於我們翻譯的疏漏，給各位讀者「抗生素也對立百病毒有用嗎？」的錯誤觀念，要特別更正並致歉。

2. 另一個會造成誤會的言論，藥品可及性基金會（Access to Medicine Foundation）以及 WTO 提出警告的公衛風險中，會產生抗藥性的並不只「立百病毒」，還有「多重抗藥性結核桿菌」（MDR-TB）、抗藥性人類免疫不全病毒（HIVDR），以及裂谷熱、茲卡病毒等缺少有效新藥的傳染病。

原文將「抗生素抗藥性」（AMR）只跟「立百病毒」做連結的處置，過度限縮了藥品可及性基金會的警告，在此要加以澄清，不是只有「立百病毒」有抗藥性的問題喔！

感謝各位網友的批評指教！

⦿ WHO 對於 AMR 的說明：
https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance

⦿ 《衛報》系列報導：
https://www.theguardian.com/science/2021/jan/26/pharmaceutical-giants-not-ready-for-next-pandemic-report-warns

⦿ 藥品可及性基金會 網站：
https://accesstomedicinefoundation.org
　
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資深駐美特派記者范琪斐，一個生活在紐約二十多年的臺灣媒體人，長期觀察臺美兩地文化差異。Podcast節目《說故事的人》各大平台皆可收聽。
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antifungal drugs 在 小小藥罐子 Facebook 的最佳貼文

小小藥罐子 By 小小藥罐子

2020-03-19 18:01:34 有 743 人按讚
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【保健知多D】薑黃素＝？？？

近月武漢肺炎肆虐香港，藥罐子相信大家時刻都已經勤洗手和戴口罩防疫。
　　
除此之外，其實不論有沒有武漢肺炎，大家都應該提升免疫力，打造一個健康的身體。
　　
過往很多人平常都可能會選擇攝取維生素C(Vitamin C)補充劑提高抵抗力。
　　
不過除此之外，其實還有薑黃素(Curcumin)提升免疫力。
　　
好，簡單介紹一下薑黃素：
　　
首先顧名思義，薑黃素主要源自薑黃(Turmeric)。
　　
至於薑黃的莖既可食用，又可藥用；既可以拿來做咖哩，在阿育吠陀(Ayurveda)這門源自印度的醫學裡，一般相信又可以拿來改善消化、紓緩關節炎(Arthritis)。
　　
實際上，薑黃裡面的薑黃素有抗菌、抗病毒、抗真菌的功能[1]，例如抗藥性金黃葡萄球菌(Methicillin-Resistant Staphylococcus Aureus, MRSA)[2]、幽門螺旋桿菌(Helicobacter pylori, H. pylori)[3]、單純疱疹一型病毒(Herpes Simplex Virus Type 1, HSV-1)[4]，在相當程度上，間接提升免疫力。
　　
除此之外，薑黃素還能夠調節人體的免疫系統並阻斷發炎組織的環氧化酶-2(Cyclo-oxygenase-2, COX-2)的形成[5]，發揮抗發炎的功能，從而有可能抑制關節炎。[6]
　　
過往有研究曾經比較薑黃與Ibuprofen這種非類固醇消炎止痛藥(Non-steroidal Anti-inflammatory Drugs, NSAIDs)在膝部退化性關節炎(Knee Osteoarthritis)的效果與安全性並顯示兩者看來在效果與安全性上沒有明顯差異。[7]

同時薑黃素還是一種抗氧化劑(Antioxidant)[8]，主要用來KO體內的自由基(Free Radicals)，理論上，能夠預防癌症。[9]
　　
除此之外，薑黃素還能夠增加黏液素(Mucin)分泌[10]，或許能夠保護胃壁，達到健胃的功效，實際上，有研究指出薑黃素能夠紓緩消化不良(Dyspepsia)的症狀。[11]
　　
在副作用上，薑黃被美國食品藥物管理局(U.S. Food and Drug Administration, FDA)列為「一般安全(Generally Recognized As Safe, GRAS)」，而且一般相信薑黃素較沒有毒性[12][13]，常見的副作用主要是胃痛，問題一般不大。
　　
話雖如此，不過有證據顯示不論是攝取高劑量薑黃還是長期攝取薑黃，兩者都可能會影響肝功能[14][15]，所以未必適合肝功能不佳人士，例如肝病。

#提升免疫力 #消炎殺毒 #補薑夠薑 #保護自己 #做多一步 #夠薑抗逆 #健康隨傳隨到 #薑黃素

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Reference:
1. Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864.
2. Mun SH, Joung DK, Kim YS, Kang OH, Kim SB, Seo YS, et al. Synergistic antibacterial effect of curcumin against methicillin-resistant Staphylococcus aureus. Phytother Res. 2013;19:599-604.
3. De R, Kundu P, Swarnakar S, Ramamurthy T, Chowdhury A, Nair GB, et al. Antimicrobial activity of curcumin against Helicobacter pylori isolates from India and during infections in mice. Antimicrob Agents Chemother. 2009;53:1592-7.
4. Zandi K, Ramedani E, Mohammadi K, Tajbakhsh S, Deilami I, Rastian Z, et al. Evaluation of antiviral activities of curcumin derivatives against HSV-1 in Vero cell line. Nat Prod Commun. 2010;5:1935-8.
5. Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol. 2009;41:40-59.
6. Srimal RC, Dhawan BN. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol. 1973;25:447–52.
7. Kuptniratsaikul V, Thanakhumtorn S, Chinswangwatanakul P, Wattanamongkonsil L, Thamlikitkul V. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. 2009;15(8):891-897.
8. Sreejayan N, Rao MNA. Free radical scavenging activity of curcuminoids. Arzneimittelforschung. 1996;46:169-171.
9. Shukla PK, Khanna VK, Khan MY, Srimal RC. Protective effect of curcumin against lead neurotoxicity in rat. Hum Exp Toxicol. 2003;22:653-8.
10. Lee CJ, Lee JH, Seok JH, Hur GM, Park YC, Seol IC, et al. Effects of baicalein, berberine, curcumin and hesperidin on mucin release from airway goblet cells. Planta Med. 2003;69:523-6.
11. Thamlikitkul V, Bunyapraphatsara N, Dechatiwongse T, et al. Randomized double blind study of Curcuma domestica Val . for dyspepsia. J Med Assoc Thai. 1989;72:613-620.
12. Ammon HPT, Wahl MA. Pharmacology of Curcuma longa . Planta Med. 1991;57:1-7.
13. Shankar TNB, Shantha NV, Ramesh HP, et al. Toxicity studies on turmeric (Cucurma longa): acute toxicity studies in rats, guinea pigs and monkeys. Indian J Exp Biol. 1980;18:73-75.
14. Deshpande S, et al. Subchronic oral toxicity of turmeric and ethanolic turmeric extract in female mice and rats. Toxicology Letters. 1998;95:183-193.
15. Kandarkar SV, Sawant SS, Ingle AD, et al. Subchronic oral hepatotoxicity of turmeric in mice--histopathological and ultrastructural studies. Indian J Exp Biol. 1998;36:675-679.

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小小藥罐子

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本網誌旨在分享用藥知識，圖文僅供教育用途。 內容僅供參考，絕對不能用來自行診治。 本網誌致力確保內容準確，惟醫藥知識隨時更新，故對內容的準確性、完整性、及時性、適用性不會承擔任何責任。如有健康疑難，請盡快求醫，以免貽誤治療良機。部分內容涉及醫藥知識，可能會引起不安，敬請留意。
一個小小的藥劑師， 一個小小的用藥資訊平台。 著作：《藥事知多D》、《用藥知多D》、《藥房事件簿》、《家居藥物攻略》
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社群媒體上有些相關的討論：

antifungal drugs 在 Pharmacology – ANTIFUNGAL DRUGS (MADE EASY) 的推薦與評價

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Antifungals are a class of drugs used for the treatment of systemic and superficial fungal infections.Most antifungal drugs interfere with ... ... <看更多>

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#48. Antifungal Drugs | The Medical Letter, Inc.

Azole antifungal agents inhibit synthesis of ergosterol, an essential component of the fungal cell membrane. FLUCONAZOLE — Fluconazole (Diflucan ...

#49. Pharmacokinetics and pharmacodynamics of antifungal drugs ...

Providing an adequate exposure to antifungal drugs is a crucial aspect of the treatment of invasive fungal infections.

#50. Antifungal Drugs Market Size, Growth | Industry Report, 2023

Antifungal Drugs Market by Drug Type [Echinocandins {Caspofungin, Micafungin, Anidulafungin, and Others}, Azoles {Imidazoles, Voricanazole, Thiazoles, ...

#51. Antifungals - Knowledge @ AMBOSS

Antifungals are a class of medications that destroy or inhibit the growth of fungal organisms and are, accordingly, used to treat fungal ...

#52. Antifungal medicines - Allerton Road Medical Centre

clotrimazole; econazole; miconazole; terbinafine; fluconazole; ketoconazole; amphotericin. How antifungal medicines work. Antifungal medicines work by either:.

#53. NHS 111 Wales - Health A-Z : Antifungal drugs

Antifungal medicines are used to treat fungal infections, which most commonly affect your skin, hair and nails. You can get some antifungal ...

#54. Common antifungal drugs in the market and their cellular targets

In spite of a plenty of antifungal drugs currently exist in the commercial pharmacies, the propagation of antifungal drug resistance and invasive type fungal ...

#55. Effectiveness of four oral antifungal drugs (fluconazole ...

Clinical trials comparing effectiveness of 4 main oral antifungal drugs are not available. We tested effectiveness of oral fluconazole, ...

#56. Antifungal Drugs: Major Types & Functions - Study.com

Antifungal drugs treat infections by killing or stopping the growth of fungi in the body. Learn the major types of antifungals and how they.

#57. Miscellaneous antifungal medications | Osmosis

Antifungal agents are a class of medications used to treat mycoses, or fungal infections. Mycoses can be superficial, meaning they are localized on the skin, or ...

#58. Antifungals for Integumentary Disease - Pharmacology - MSD ...

The antifungal drugs used most commonly to treat integumentary diseases are ... Ketoconazole is a synthetic, broad-spectrum antifungal drug belonging to the ...

#59. Susceptibility Testing of Fungi to Antifungal Drugs - MDPI

Susceptibility testing of fungi against antifungal drugs commonly used for therapy is a key component of the care of patients with invasive fungal ...

#60. Antifungal medicines - Practitioner Health

clotrimazole; econazole; miconazole; terbinafine; fluconazole; ketoconazole; amphotericin. How antifungal medicines work. Antifungal medicines work by either:.

#61. Voriconazole: MedlinePlus Drug Information

Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection.

#62. Antifungals - Infectious Disease Advisor

What is the impact of antifungals on the prevention and control of health ... there is no a clear indication for the combined use of antifungal drugs, ...

#63. Medical Definition of Antifungal drug - MedicineNet

Examples of antifungal drugs include miconazole (MONISTAT) and clotrimazole (LOTRIMIN, MYCELEX). SLIDESHOW. Nail Disorders: What Nails Say About ...

#64. A review of selected systemic antifungal drugs for use in dogs ...

Although griseofulvin is the only antifungal approved for systemic administration by the Food and Drug Administration (FDA) for veterinary ...

#65. Therapeutic Drug Monitoring of Antifungal Drugs - SpringerLink

Adequate treatment of invasive fungal infections (IFIs) requires proper drug selection and proper dosing of antifungal drugs. Triazoles or ...

#66. Mode of Action of Antifungal Drugs - Microbiology Info.com

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Learn more!

#67. Cipla Antifungal Drugs - Latest Price, Dealers & Retailers in ...

Find here Cipla Antifungal Drugs dealers, retailers, stores & distributors. Get latest prices, models & wholesale prices for buying Cipla Antifungal Drugs.

#68. BNF 5.2: Antifungal drugs | OpenPrescribing

High-level prescribing trends for Antifungal drugs (BNF section 5.2) across all GP practices in NHS England for the last five years.

#69. Oral antifungal drugs for treating athlete's foot (tinea pedis)

This review compared different oral antifungal drugs (i.e. drugs taken by mouth), and it included 15 trials, involving 1438 participants. There ...

#70. Antifungal drug dosing adjustment in critical patients with ...

Antifungal drug dosing adjustment in critical patients with invasive fungal infections. Athina Pyrpasopoulou 1,2, Elias Iosifidis 1,3, ...

#71. Topical Treatment of Common Superficial Tinea Infections

Common Antifungal Medications and Their Forms ; Ciclopirox (Loprox; Penlac||). Rx. Lacquer ; Clotrimazole (Lotrimin). OTC. Yes ; Miconazole ( ...

#72. 3.15 Antifungals – Nursing Pharmacology - WI Technical ...

Allylamines, a structurally different class of synthetic antifungal drugs, ... The drug amphotericin B is used for systemic fungal infections like ...

#73. Nail Infection: Should I Take Antifungal Pills? - MyHealth ...

How well do antifungal pills work? Pills to treat fungal nail infections include terbinafine (Lamisil) and medicines called azoles, such as itraconazole ( ...

#74. Pharmacology of azoles - UpToDate

Azole antifungal agents have added greatly to the therapeutic options for ... and putative targets for antifungal drug development.

#75. ASDCD: Antifungal Synergistic Drug Combination Database

Traditional antifungal drugs with single targets have been reported to cause serious side effects and drug resistance.

#76. Antifungal drug - wikidoc

List of antifungal drugs. Antifungals work by exploiting differences between mammalian and fungal cells to kill off the fungal organism ...

#77. Antifungal Drug Development: Challenges, Unmet Clinical ...

The azoles are the most widely used class of antifungal drugs (Lass-Flörl 2011). Although there are many azoles currently available (Fig. 2), fluconazole, ...

#78. The fight against fungi - C&EN

Krysan and other scientists who work on drugs for pathogenic fungi point out that it's been 20 years since a drug in a new class of antifungals, ...

#79. Over-the-Counter Antifungal Medications for Athlete's Foot

Terbinafine · Clotrimazole · Tolnaftate · Miconazole · Undecylenic Acid · How to Use Topical Antifungal Medications · When to See a Healthcare ...

#80. List of drugs/medicine used for Fungal Infections ... - Medindia

Flucytosine is an antifungal agent, prescribed for serious infections (eg- candida, meningitis and pulmonary infections) caused by certain fungi either alone or ...

#81. Antifungal Drugs, Topical | Encyclopedia.com

Topical antifungal drugs are preparations applied to the skin, nails or mucous membranes to treat infections caused by fungi.

#82. Antifungal drugs in pregnancy: a review

will review available data regarding the safety of antifungal drug use in ... in maternal renal blood flow impact on the renal clearance of many drugs.

#83. Antifungal drug resistance to azoles and polyenes - The Lancet

Among the new antifungal drugs, inhibitors of beta glucan synthesis and second-generation azole and triazole derivatives have characteristics ...

#84. Systemic Antifungals and Common Interactions

When using topical antifungal drugs, patients must be aware of common ... Systemic antifungals, however, increase the need to consider drug ...

#85. Antifungal Drugs

Antifungal drugs - Classification (5). 1. ANTIBIOTICS. Amphotericin B, (AMB), Nystatin,. Hamcyin, Natamycin. Griseofulvin. 2. ANTIMETABOLITES:.

#86. Systemic Antifungal Therapy: Past, Present and Future

Fluconazole is also a new triazole antifungal drug which has the best pharmacokinetics profile and least incidence of adverse effects ...

#87. The Fungus Among Us: An Antifungal Review - US Pharmacist

Besides the general azole class adverse reactions, ketoconazole also carries a black box warning for hepatotoxicity and has significant drug– ...

#88. Nail Infection: Should I Take Antifungal Pills? - Michigan ...

How well do antifungal pills work? Pills to treat fungal nail infections include terbinafine (Lamisil) and medicines called azoles, such as itraconazole ( ...

#89. Antifungal Drugs Industry Trends & Opportunities - Grand ...

Rising incidence of fungal infections is the key contributing factor expected to propel the growth of the antifungal drugs market over the forecast period.

#90. The polyene antifungals, amphotericin B and nystatin, cause ...

There is a pressing need to identify novel antifungal drug targets to aid in the therapy of life-threatening mycoses and overcome increasing ...

#91. 1-24 of 851 results for "Antifungal Medicine" - Amazon.com

Online shopping for Health & Household from a great selection of Athletes Foot Remedies, Nail Fungus Treatments, Jock Itch Treatments ...

#92. Improving Value in Specialised Services Antifungal ...

spend on antifungal medicines – this includes preserving the future ... Whilst resistance to antifungal drugs is not as common as that seen with ...

#93. CHEBI:87069 - imidazole antifungal drug - EMBL-EBI

ChEBI Name, imidazole antifungal drug. ChEBI ID, CHEBI:87069. Definition, Any imidazole antifungal agent that has been used for the ...

#94. Higher rates of miscarriage could be caused by oral antifungal ...

Published in CMAJ, new research has found that oral antifungal drug used to treat yeast infections is linked to higher rates of miscarriage.

#95. Superficial mycoses in Belgium: Burden, costs and antifungal ...

Background Monitoring of superficial mycoses requires more attention due to their important incidence, health costs and antifungal drugs ...