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#1. 研究服務| 鼎捷生技有限公司
長鏈非編碼RNA(Long non-coding RNA, lncRNA)是一類長度大於200 nt且不表現出蛋白質編碼潛能的RNA,參與了X染色體沉默,基因組印記以及染色質修飾,轉錄激活,轉錄 ...
#2. 長鏈非編碼核糖核酸- 維基百科
長鏈非編碼核糖核酸[編輯] · 長鏈非編碼核糖核酸(英語:long non-coding RNAs,簡稱為lncRNA)指的是長於200 · 近年研究顯示 · 目前將哺乳動物基因組的全景描繪為:長段的 ...
#3. Long Non-Coding RNAs (lncRNA)簡介 - 有勁的基因資訊- 痞客邦
a. lncRNA HOTAIR,Xist,RepA,Kcnqot1會促使Polycomb complex調控X染色體進行Chromatin remodeling (X異染色質生成,抑制其上面的基因表現)。 b. 以基因 ...
lncRNA ,意即長鏈非編碼RNA(long non-coding RNA),通常指的是長度大於200 bp、不產生蛋白質的RNA。不過近來的研究發現有些lncRNA 也會像mRNA 一樣被剪接,少數更會 ...
#5. Gene regulation by long non-coding RNAs and its biological ...
Early studies indicated that lncRNA genes likely contain fewer exons than mRNAs. The recently developed RNA capture long seq enabled better ...
#6. Databases and In Silico Tools for lncRNA Analysis - PubMed
The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis. Noncoding RNA. 2020 Dec 16;6(4):49. doi: 10.3390/ncrna6040049.
#7. What is Long non-coding RNA (lncRNA)? | 香港城市大學
What is lncRNA? The central dogma of molecular biology is “DNA (deoxyribonucleic acid) makes RNA, RNA makes proteins, and proteins make us”. The ...
#8. Reconstruction and Analysis of the lncRNA-miRNA-mRNA ...
Recent studies have suggested that long non-coding RNA (lncRNA) can interact with microRNA (miRNA) and indirectly interact with mRNA through ...
Stand-‐alone lncRNAs (lincRNAs) : RNA Pol II, polyadenylated, and. Known examples include Xist (Brockdorff et al. 1992; Brown et al. 1992).
#10. Long Noncoding RNA - an overview | ScienceDirect Topics
Long noncoding RNAs (lncRNAs) are RNA molecules larger than 200 nucleotides. They regulate gene expression at transcriptional, RNA processing, translational, ...
#11. LNCcation: lncRNA localization and function - Rockefeller ...
Bridges et al. discuss current knowledge, lingering questions, and emerging themes surrounding lncRNA subcellular localization and its ...
#12. HERES, a lncRNA that regulates canonical and noncanonical ...
Here, we describe a long noncoding RNA (lncRNA), HERES, that epigenetically regulates both canonical and noncanonical Wnt signaling pathways in ...
#13. lncATLAS
Only GENCODE-annotated lncRNA genes are present, and may be accessed using their identifier (ENSG...) or official Gene Name. The localisation of your ...
#14. lncRNA Expression, In Situ Hybridization | ACDBio
RNAscope ® in situ assays will undoubtedly accelerate lncRNA research and become an indispensable tool for lncRNA-based molecular diagnostics. Some of the ...
#15. A small protein encoded by a putative lncRNA regulates ...
The human genome harbors thousands of long noncoding RNA (lncRNA) genes transcribed into a heterogeneous group of transcripts > 200 nucleotides ...
#16. Long Non-Coding RNA (LncRNA) - BioCat GmbH
Long Non-Coding RNA (LncRNA) ... Long noncoding RNAs (LncRNAs) are emerging as master regulators of embryonic pluripotency, differentiation, patterning of the ...
#17. RT2 lncRNA PCR Arrays - QIAGEN
RT 2 lncRNA PCR Arrays. For lncRNA expression analysis by pathway and disease using laboratory-verified SYBR ® Green qPCR assays. Features.
#18. Functional annotation of lncRNA in high-throughput screening
(A) Methods for modulating lncRNA expression levels, by cleavage of the RNA directly, modulating the transcription, and knockout of the gene. (B) ...
#19. 基因也環保?! 長鏈非編碼RNA 的誕生| GeneOnline News
新的lncRNA 基因從何而來?至少有兩個可能。一種方式是無中生有:如果一段本來不會表現的DNA,偶然獲得會轉錄出RNA 的能力,就 ...
#20. LncSEA: a platform for long non-coding RNA related sets and ...
Using reference lncRNA sets, enrichment analyses will be useful for analyzing lncRNA lists of interest submitted by users. Therefore, we developed a human ...
#21. Long non-coding RNA (LncRNA) classification in the context ...
Download scientific diagram | Long non-coding RNA (LncRNA) classification in the context of different genomic locations. On the basis of genomic location ...
#22. From structure to function: Route to understanding lncRNA ...
Thus, gaining comprehensive understanding of lncRNA modes of actions might benefit from RNA structural analysis. Below, we will introduce some ...
#23. LNCRNA-ATB RNA Gene - GeneCards
Complete information for LNCRNA-ATB gene (RNA Gene), Long Noncoding RNA Activated By TGF-Beta, including: function, proteins, disorders, ...
#24. Long Non-coding RNA Sequencing (lncRNA-seq) - Novogene
How does lncRNA sequencing work? · Profiling known and novel transcripts and identifies variations · Predicting targeting genes of lncRNA · Identifying biomarkers ...
#25. LncRNADisease database - the Cui Lab
In addition, LncRNADisease also curated lncRNA interactions in various levels, including protein, ... NRED: a database of long noncoding RNA expression.
#26. Cells | Special Issue : lncRNA and Cancer - MDPI
LncRNAs can also have roles in the post-transcriptional regulation of gene expression, such as MALAT1 in splicing and lincRNA-p21 in translation. LncRNA ...
#27. lncRNA qPCR Profiling | System Biosciences
miRNA & lncRNA Research Tools · Lenti-miR Precursor Vectors · Lenti-miR Libraries · miRZip Knockdown Vectors · miRNA qPCR Profiling · LncRNA qPCR Profiling.
#28. The emerging role of the long non-coding RNA HOTAIR in ...
Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol. J Mol Biol. 2013;425(19):3707–22. CAS PubMed ...
#29. The Long Noncoding RNA HEAL Regulates HIV-1 Replication ...
lncRNA loci can regulate gene expression in a cis or trans manner, and these classifications provide a basic framework to design experimental ...
#30. Genome-wide analysis of lncRNA stability in human - PLOS
However, little is known about the features related to human long noncoding RNA (lncRNA) stability. By inhibiting transcription and collecting ...
#31. 长非编码rna_百度百科
长链非编码RNA(Long non-coding RNA, lncRNA)是长度大于200 个核苷酸的非编码RNA。研究表明, lncRNA 在剂量补偿效应(Dosage compensationeffect)、表观遗传调控、细胞 ...
#32. De-repressing LncRNA-Targeted Genes to Upregulate Gene ...
We suggest that small molecule modulators of a novel class of drug targets, lncRNA-protein interactions, have great potential to treat some cancers, ...
#33. What's the Difference Between lncRNA and lincRNA? - G ...
Long intergenic non-coding RNA (lincRNA) and long non-coding RNA (lncRNA) are two novel RNA molecules that contain about 200 nucleotides in ...
#34. lncRNA RT-qPCR Workflow | Bio-Rad Laboratories
Our innovative long noncoding RNA (lncRNA) workflow enables highly sensitive detection of lncRNAs by RT-qPCR. The workflow was developed to overcome ...
#35. LNCipedia
LNCipedia is a public database for long non-coding RNA (lncRNA) sequence and annotation. The current release contains 127,802 transcripts and 56,946 genes.
#36. lncRNA Blog – lncRNA Research and Industry News
lncRNA Discovery Timeline. Exponential discovery of lncRNAs with the adoption of transcriptome-wide gene expression technologies ...
#37. Long Non-Coding RNA Sequencing - Yourgene Health
Long Non-Coding RNAs (lncRNA)是一種不編碼蛋白的轉錄本,長度通常大於200nt,最長可超過10,000nt的RNA分子。早期研究人員認為轉錄體主要由mRNA所組成,並且 ...
#38. LncRNA Research Resources - Labome
LncRNA refers to long non-coding RNA molecules, usually greater than 200 bases, and with features similar to mRNA, such as 5' capping, splicing, ...
#39. Modulating the expression of long non‐coding RNAs for ...
Elucidating lncRNA function is also complicated by the genomic arrangement of lncRNAs. Many lncRNAs overlap with coding genes (both in the sense and in the ...
#40. High-throughput functional analysis of lncRNA core promoters ...
Abstract. Transcription initiates at both coding and noncoding genomic elements, including mRNA and long noncoding RNA (lncRNA) core ...
#41. The Role of Long Noncoding RNAs in Gene Expression ...
We also introduce the interaction between lncRNA and DNA, RNA and protein, and the bioinformatics applications on lncRNA research.
#42. LncSpA: LncRNA Spatial Atlas of Expression across Normal ...
Long noncoding RNAs (lncRNA) play important roles in maintaining morphology and function of tissues, and their regulatory effectiveness is ...
#43. Bioinformatics-Based Identification of lncRNA-miRNA-mRNA ...
Bioinformatics-Based Identification of lncRNA-miRNA-mRNA Network in Dilated Cardiomyopathy and Drug Prediction. Wei Liu , 1 Jinqiang Cai , 2 Mengjie Tang, 3 and ...
#44. Platforms for Investigating LncRNA Functions - SAGE Journals
Long noncoding RNA (lncRNAs) interactome and strategies. The lncRNA interactome is complex and involves DNA, RNA, and/or proteins. It is ...
#45. Silencer Select siRNAs for Long Non-Coding RNAs - Thermo ...
To help overcome this, Silencer Select lncRNA siRNAs for lncRNA include the following: Locked nucleic acid (LNA) technology helps ensure high specificity and ...
#46. Long Non-coding RNA Sequencing (LncRNA-Seq) Service
Based on our advanced SuPrecision™ platform, Creative Biolabs has accumulated extensive experience in lncRNAs sequencing (LncRNA-seq).
#47. Long Noncoding RNA Discovery in Cardiovascular Disease
eRNA indicates enhancer RNA; and lncRNA, long noncoding RNA. In general, enhancer RNAs are thought to be unstable, unspliced, nonpolyadenylated, ...
#48. Identifying lncRNA Biomarkers in Highly Fragmented RNA ...
Identifying lncRNA Biomarkers in Highly Fragmented RNA Samples. Optimizing NextSeq 500 System and TruSeq RNA Exome Kit RNA sequencing workflows for lncRNA ...
#49. Current strategies to knockdown long non-coding RNAs
The location of the primary reservoir of a lncRNA can impact the ability to knock down expression levels of that species. Three strategies are commonly used to ...
#50. Understanding the Long Noncoding Transcriptome
Learn about the exciting new field of long noncoding RNA (lncRNA) and how this newly discovered class of RNA compares to messenger RNA ...
#51. LncRNA Sequencing - CD Genomics
LncRNAs are widely distributed in organisms and lncRNA transcripts account for the major part of the non-coding transcriptome. LncRNAs may be ...
#52. LncRNAWiki - National Genomics Data Center
... open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase.
#53. A lncRNA Signature in Esophageal Squamous Cell Carcinoma
Recent studies also indicate that lncRNA can play a regulatory role in complex networks of autophagy by interacting with multiple ...
#54. Analysis of long non-coding RNA (lncRNA) expression in ...
Analysis of long non-coding RNA (lncRNA) expression in hepatitis B patients. Sunde Yılmaz Susluer Department of Medical Biology, Faculty of ...
#55. Emerging mechanisms of long noncoding RNA function ...
lncRNA -modulated effectors include regulators of transcription, chromatin organization, RNA processing, and translation, such that lncRNAs can influence gene ...
#56. How to Study LncRNA Expression and Modifications? | Arraystar
Why use microarray over seq for lncRNA profiling; Why lncRNA m6A modification is important; What is the best way to profile lncRNA modification; The latest ...
#57. HOTAIR: An Oncogenic Long Non-Coding RNA in Human ...
Structure and genomic location of lncRNA HOTAIR, and association with a variety of human cancers. HOTAIR gene is located HoxC gene cluster from ...
#58. 長鎖ノンコーディングRNAのさまざまな機能 | 理化学研究所
lncRNA の一部は、転写や翻訳、エピジェネティクスの制御などを介して、細胞の分化やがん化、個体発生や疾患など、生体の多様なプロセスに関与することが知 ...
#59. 一文读懂长非编码RNA(lncRNA)的分类、功能及测序鉴定方法
RNA的重要调控功能发现历程(Rinn et al. Annu Rev Biochem, 2013). 长非编码RNA,英文名为long noncoding RNAs,缩写为lncRNA,是指长度大于200 核 ...
#60. WGLab/lncScore: A python package for the ... - GitHub
lncScore is a python package for the identification of lncRNA from the assembled novel transcripts, and it also can be used to calculate the coding ...
#61. Long non-coding RNA (Lnc RNA) - News Medical
Discover lncRNA: Understanding the Long Noncoding Transcriptome Play. Stand-Alone Lnc RNA. These sequences are present in between the coding ...
#62. 암에서 lncRNA (long noncoding RNA)의 역할과 기능 연구 동향
lncRNA 는 200 nt 이상의 길이로 구성된 비암호화 RNA이다. lncRNA는 인체의 자연적인 현상으로 존재하는 RNA이지만, 암과 같은 특정 질병에서 발현량 ...
#63. Comparison of lncRNA and mRNA expression in mouse ...
But the role of lncRNAs involved in RABV infection is still elusive. In this study, we performed global transcriptome analysis of both of lncRNA ...
#64. 从实验到分析——深度解析基于二代测序的LncRNA研究及应用 ...
非编码RNA起初被认为是基因组转录的“垃圾”,而近年来,多个高水平的杂志以封面形式报道长链非编码RNA(long non-coding RNA,LncRNA)的重要性,由此LncRNAs引起了人们 ...
#65. lncRNA的世界,你是了如指掌還是毫無頭緒?
長鏈非編碼RNA(long noncoding RNA,lncRNA)是一類不編碼蛋白的RNA分子,長度在200bp以上;研究表明,lncRNA具有保守的二級結構,可以與蛋白、DNA和RNA ...
#66. Long non-coding RNAs (lncRNAs) and their transcriptional ...
Better understanding of lncRNA regulation of inflammation will provide novel targets for the development of new therapeutic strategies.
#67. LncRNA MAGI2-AS3 suppresses the proliferation and ...
OBJECTIVE: To uncover the biological role of long non-coding RNA (lncRNA) MAGI2-AS3 in the progression of non-small cell lung carcinoma (NSCLC) and its.
#68. Epigenomics and the Role of Long Non-coding RNAs - iBiology
Part 2: LncRNA Function at the RNA Level: Xist ... These regulatory elements can confer functionality to lncRNA genes. Chang shares the research story of a ...
#69. Long Non Coding RNA Biology - 第 19 頁 - Google 圖書結果
The high specificity of lncRNA expression argues in favor of important regulatory roles that these molecules can play in different biological contexts, ...
#70. lncRNA and cancer - Weconext
#71. lncRNA:バイオキーワード集|実験医学online
siRNA, miRNA, piRNAなどのsmall RNAに対し,100~200塩基以上のncRNAを一般的にlncRNAと呼んでいる.lincRNA等の遺伝子間領域をはじめ,Tsixのようなアンチセンス遺伝子, ...
#72. Papel de los lncRNA como potenciales biomarcadores y ...
Los lncRNA incluyen a todos los ncRNA de más de 200 nucleótidos de longitud por lo que se trata de un grupo muy heterogéneo de moléculas que ...
#73. The functions of long noncoding RNAs in development and ...
Overall, the sequences of lncRNA exons are only marginally better conserved than those in the introns of protein-coding genes or in random ...
#74. Intelligent Computing Theories and Application: 15th ...
So far, various lncRNA-related biological databases are available free of charge [3, 4]. However, experimentally verified disease-associated lncRNAs are ...
#75. 長鏈非編碼RNA(Long non-coding RNA, lncRNA)是長 - 華人百科
人們對lncRNA(Long noncoding RNAs, LncRNAs) 的認識還處在初級階段,lncRNA起初被認為是基因組轉錄的"噪音",是RNA聚合酶II轉錄的副產物,不具有生物學功能。
#76. HOXBLINC long non-coding RNA activation promotes ...
Our study reveals that HOXBLINC lncRNA activation plays an essential oncogenic role in NPM1c+ leukemia. HOXBLINC and its partner MLL1 are ...
#77. Predict lncRNA's DNA binding domains and binding sites Beta
Welcome to lncRNA.smu.edu.cn ! This website currently consists of two software – LongTarget and LongMan. LongTarget was developed to predict a lncRNA's DNA ...
#78. Encyclopedia of Bioinformatics and Computational Biology: ...
been thoroughly established in previous studies, it is now possible to catalogue and curate high-confidence lncRNA (Pauliet al., 2012).
#79. Mauro Calabrese - The Bioinformatics CRO Podcast
Mauro Calabrese, Associate Professor at UNC Chapel Hill, discusses the future of RNA-based therapeutics and the role of lncRNA in gene ...
#80. lncRNA與癌症_生信技能樹- 微文庫
例如,lncRNAs可以與多梳蛋白複合體結合來調控癌症發生。PRC1和2是已知的致癌基因,能夠導致許多惡性腫瘤的發生。FAL1 lncRNA 與PRC1的亞基BMI1結合。在 ...
#81. “三多”lncRNA有这3条经典分析思路 - 网易
不同来源的lncRNA也有不同的功能,比如Antisense的lncRNA可能会影响其基因组位置上编码的mRNA发生可变剪接。这些lncRNA虽然整体保守性不如mRNA,但它们的 ...
#82. The Role of ncRNAs in Solid Tumors Prognosis: From ...
have revealed that lncRNA plays an important role in the process of tumor development. Zhang et al. and Song et al. have reported, respectively, ...
#83. Deficiency of lncRNA SNHG12 impairs ischemic limb ...
JCI Insight. 2021 Nov 18:e150761. doi: 10.1172/jci.insight.150761. Online ahead of print.ABSTRACTSNHG12, a long non-coding RNA (lncRNA) ...
#84. 과학기술 지식인프라 ScienceON
LncRNA expression profile of ΔNp63α in cervical squamous cancers and its suppressive effects on LIF expression 인용. Cytokine v.96 , 2017년, pp.114 - 122. Qian, ...
#85. Long Non-coding RNA: The Dark Side of the Genome
Initial structural analyses of lncRNA in the cancer transcriptome ... of SNP or somatic mutations in lncRNA associated with cancer (Chu et al., 2015; ...
#86. lncRNA机制1 - 调控临近基因表达- 上_哔哩哔哩 - BiliBili
#87. Team Shares Chinese Genome Resource, Population ...
... nearly 3,800 long noncoding RNA, or lncRNA, splice variants, ... of loss-of-function variants for protein-coding and lncRNA genes in ...
#88. New prognostic biomarkers and cancer-driving genes found in ...
Within their catalogue, the researchers zeroed in on one lncRNA, called HOXA10-AS, that their initial machine learning analysis revealed was ...
#89. Four trains cancelled | Thiruvananthapuram News - Times of ...
'LncRNA impacts cancer cure'. Thiruvananthapuram: As the track restoration work is progressing at locations where landslip occurred in the ...
#90. LncRNAs的详细注释和功能分析 - 康成生物
一站式Arraystar lncRNA芯片技术服务包含系统而详细的lncRNA注释、子类分析等重要分析项目,这些信息有助于揭示lncRNAs复杂的生物学功能。通过研究发现,lncRNAs在凋 ...
#91. [유전학 중요개념 정리] Long intergenic non-coding RNA ...
마지막으로 lncRNA에 대한 정보를 포함하는 대표적인 Database를 소개하면서 포스팅을 마무리하고자 합니다. 아직 많은 부분이 밝혀져 있지 않아서, ...
#92. Prof M R S Rao delivers 26th RGCB Foundation Day lecture
... Prof Rao, a Padma awardee, said clinical trials are currently going on for several LncRNA molecules that have a significant impact on ...
#93. Descubren nuevos biomarcadores del cáncer en la 'materia ...
La falta de expresión de este lncRNA se asoció a tumores cerebrales de bajo riesgo y la alta expresión a tumores agresivos. "Estamos ...
#94. Non-coding RNAs have great therapeutic potential in cancer ...
... on for several LncRNA molecules that have a significant impact on cancer ... and cancer - A story of LncRNA mRHL: Discovery to Function.
#95. Investigating the Dynamics of Epigenetic Plasticity in Cancer ...
During her Post-Doc years Céline Vallot worked on the inactive X chromosome. Using RNA-Seq she discovered a novel long noncoding RNA (lncRNA) ...
#96. 科技部公布52起科研诚信案件调查结果 - 科学网
三、青岛大学附属医院郭彩宏为通讯作者、曹艺巍为第一作者的论文“LncRNA ATB promotes proliferation and metastasis in A549 cells by ...
#97. Human assembly and gene annotation - Ensembl
This site provides a data set based on the December 2013 Homo sapiens high coverage assembly GRCh38 from the Genome Reference Consortium. This assembly is used ...
lncrna 在 WGLab/lncScore: A python package for the ... - GitHub 的推薦與評價
lncScore is a python package for the identification of lncRNA from the assembled novel transcripts, and it also can be used to calculate the coding ... ... <看更多>